Rearrangement Reactions in Organic Chemistry
Rearrangement Reactions in Organic Chemistry Rearrangement reactions are one of the important class of organic reactions, wherein a group or bond attached to a carbon atom moves to another carbon atom often in a single molecule. Example: A-B-X → B-A-X In rearrangement reactions, the reaction may involve more than one step. No by-products would be […]
Baker-Venkataraman Rearrangement
Baker -Venkataraman Rearrangement This rearrangement reaction of organic chemistry involves the regio-selective formation of 1,3-diketones through the base-induced transfer of acyl group in O-acylated phenol ester. It is an intramolecular acyl transfer reaction via the formation of an enolate. This rearrangement reaction plays a key role in the synthesis of flavons from readily available starting […]
Benzyl-Benzilic acid Rearrangement
Benzyl-Benzilic Acid Rearrangement Rearrangement of a-diketones to a-hydroxycarboxylic acid through 1, 2-shift intramolecular rearrangement is called as a benzyl-benzylic acid reaction. This reaction helps in synthesizing a-hydroxy acids using easily available starting materials. Mechanism involving in this rearrangement reaction is,
Claisen Rearrangement
Claisen Rearrangement Sigmatropic or electrocyclic intramolecular rearrangement of aryl allyl ether in to gamma, delta-unsaturated carbonyl compound in the presence of heat or Lewis acid is known as Claisen rearrangement. Sigmatropic rearrangement involves migration of s bond from one end of p system to others. Reaction mechanism of this reaction closely resembles that of Diels- […]
Cope Rearrangement
Cope Rearrangement Thermal isomerization of 1,5-diene into regio-specific 1,5-diene is known as cope rearrangement. This rearrangement is generally reversible in nature and is key in the synthesis of complex natural products such as alkaloids, carbohydrates, etc. in organic chemistry. Mechanism of Cope and Claisen rearrangements are very similar. Anionic oxy-cope rearrangement is the reaction in […]
Fries Rearrangement
Fries Rearrangement It is an organic reaction wherein acyl phenols are formed from phenolic esters in the presence of a Lewis acid catalyst. Many of these are act as intermediates in the pharmaceutical, agricultural, thermographic and other industrial synthetic products. When the same rearrangement reaction takes place in the presence of light, it is known […]
Pinacol Rearrangements
Pinacol Rearrangements Acid-catalyzed conversion of 1,2-diols to ketones along with the elimination of water as a by-product are collectively called as pinacol rearrangements. One of such organic reaction is the formation of pinacolone (methyl tert-butyl ketone) from pinacol (2,3-dimethyl-2,3-butanediol) and is famously known as Pinacol-pinacolone rearrangement. This reaction used only occasionally to synthesize ketones […]
Classification of Organic Compounds
Classification of Organic Compounds Organic compounds are classified according to the type of elements and bonds present in the molecules. Compounds containing only carbon and hydrogen are called hydrocarbons. However organic compounds can also contain elements other than carbon and hydrogen-like oxygen, nitrogen, sulfur, phosphorus, silicon, etc. Hydrocarbons are further classified as aliphatic and aromatic […]
Methane
Methane Methane is the smallest member of the alkane family as well as all of the organic compounds. Yet, It is the most important and powerful of gases on the planet. It is formed by the anaerobic decay of plants and is a major constituent of the natural gas. It can be obtained as a […]
Chemical Properties of Methane (Oxidation)
Chemical Properties of Methane (Oxidation) Methane reacts with reactive substances under vigorous conditions. One such reactive substance is oxygen. Oxidation of methane or in other words combustion (complete) of methane (in fact for any hydrocarbon) results in formation carbon dioxide and water with release of heat. This oxidation is the major reaction occurring during the […]