Hydroxychloroquine in the Treatment of COVID-19

Hydroxychloroquine in the Treatment of COVID-19 COVID-19 global spread took the lives of many people. It is a disease relate to the respiratory system induced by SARS-CoV-2[1]. WHO proposed to take preventive measures but simultaneously authorities also required clinical trials for drugs that are effective against the coronavirus. Although, fewer patients have access to clinical […]

Factors Affecting Chemical Shift in Proton NMR Spectroscopy

Factors Affecting Chemical Shift in Proton NMR Spectroscopy Electronegativity: more electronegative element leads to deshielding of protons and signal appears at downfield and vice versa. Anisotropy effect: those compounds which are having a double or triple bond involve pi-electron which produces an induced field that may change the position of electrons and hence lead to […]

Retrosynthesis

It is an analytical technique used in which the deconstruction or fragmentation of targeted organic molecule is done to produce starting material, generally called as “synthon”. Fragments generated via a particular pattern of break down. It is called as retro synthesis because it is a reversible process of chemical synthesis. E.J Corey gave this concept […]

NMR Signal Splitting

NMR Signal Splitting In NMR, the electric field is applied to the sample and the nearby proton aligned themselves in the same or different manner to the applied field. Splitting only happens between those protons of the same carbon which are not chemically equal to each other. Two magnetic fields felt by the proton due […]

Coupling Constant

Coupling Constant It is the measurement of the distance between the peaks of a multiplet which arises after splitting. It is known as the coupling constant. It denoted by the J and its unit is Hertz. It is a useful tool in the measurement of the effectiveness of spin-spin coupling and predicting the protons NMR […]

Synthetic Polymers

Synthetic Polymers Polymers are nothing but a repeating unit of a monomer that joined together to form a large compound. It includes two reaction processes condensation and addition. When two or more single units are combined to produce a polymer that procedure is known as polymerization. This topic is best described at synthetic polymer homework […]

Heterocyclic Chemistry

Heterocyclic Chemistry Definition: Heterocyclic compounds contain nitrogen Sulphur and oxygen in the cyclic ring at the place of carbon. Hence, their common names regard them. They generally have one or more heteroatoms in the ring, and all the nucleic acids are examples of such compounds. Approximately 59 % of the drugs approved by the US […]

Author: @dmin