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Birch Reduction

Birch Reduction It is an organic chemistry reaction where the benzene ring containing aromatic compounds undergoes 1,4 reduction to produce unconjugated 1,4 cyclohexadienes. The reaction was discovered by Australian chemist Arthur Birch in the year 1944. The reaction takes place in presence of metals like lithium, sodium or potassium in liquid ammonium along with alcohol. […]

Dieckmann Condensation

Dieckmann Condensation It is a ring-forming reaction to form cyclic β- keto ester by reaction of diesters with the base. It leads to the formation of 5- and 6-membered cyclic β-keto esters via intermolecular condensation in presence of a base. The reaction was discovered by German chemistry Walter Diekmann in 1894. The reaction has a […]

Baeyer-Villiger Oxidation

Baeyer-Villiger Oxidation It is the type of organic redox reaction to form ester or lactone from a ketone or cyclic ketone respectively. The reaction takes place in presence of peroxy acid, most commonly 3-chloroperoxybenzoic acid and trifluroperacetic acid are used.The reaction was first discovered by Adolf von Baeyer and Victor Villiger in the year 1899. […]

Yamaguchi Esterification

Yamaguchi Esterification The Yamaguchi esterification is the coupling organic chemistry reaction where the ester is formed from a carboxylic acid in presence of alcohol, triethylamine, 2,4-trichlorobenzoyl chloride i.e. Yamaguchi reagent and DMAP (4-Dimethylaminopyridine). The reaction was discovered in 1979 by Masaru Yamaguchi. Mechanism of action– Firstly carboxylic acid get deprotonated by triethylamine which results into […]

Atomic Orbital Vs. Molecular Orbital

Atomic Orbital vs. Molecular Orbital Atoms are building block and smallest part of the element which reacts chemically. Atoms consist of three fundamental particles i.e. electrons, protons, and neutrons. Charged particles, electrons they move around the nucleus in well-defined circular orbit. Atoms in the group are called as a molecule, a chemical bond is present […]

Rate of Reaction

Rate of Reaction   The rate of chemical reaction is the difference in concentration of reactant or product in unit time. It could be the rate of decrease in concentration of any one of the reactants or increase of rate in concentration in case of any one of the products. Reactant (R) Product (P) The […]

Perkin Reaction

Perkin Reaction The Perkin reaction is a condensation reaction of organic chemistry. It involves the formation of α, β unsaturated carboxylic acid from aromatic aldehydes and anhydride in presence of a base catalyst which is alkali salt of the acid.   The reaction was first discovered by William Henry Perkin in the 19th century, who […]

Appel Reaction

Appel Reaction It is a type of the organic chemistry reaction to form alkyl halide directly by reaction of tetrahalomethane and triphenylphosphine and alcohol. The reaction was discovered in 1975 by Rolf Appel. Mechanism – Firstly in reaction triphenylphosphine and tetrachloromethane react to form phosphonium salt. Then deprotonation of alcohol occurs forming alkoxide followed by […]

Empirical and Molecular formula

Empirical and Molecular Formula A chemical compound is indicated in different ways in chemistry like by its common name, such as benzene or it can be indicated by its chemical formula. The chemical formula gives information of atoms specifically present in the chemical compound. The chemical formula is expressed as a molecular and empirical formula. […]

Beckmann Rearrangement Reaction

Beckmann Rearrangement Reaction It is a rearrangement reaction in which oximes are converted into amides in presence of acid. The reaction was discovered by Ernst Otto Beckmann who was German chemist. The reaction is acid catalyzed, different acids can be used like polyphosphoric acid, sulfuric acid, hydrogen fluoride, acetic acid, and hydrochloric acid. Mostly sulfuric […]